Issue
J. Phys. Colloques
Volume 47, Number C8, Décembre 1986
EXAFS and Near Edge Structure IV
Page(s) C8-1129 - C8-1136
DOI https://doi.org/10.1051/jphyscol:19868220
EXAFS and Near Edge Structure IV

J. Phys. Colloques 47 (1986) C8-1129-C8-1136

DOI: 10.1051/jphyscol:19868220

EXAFS AND XANES OF SUPEROXIDE DISMUTASE : A COPPER PROTEIN

S.S. HASNAIN1, L. ALAGNA2, N. J. BLACKBURN3 et R.W. STRANGE1, 3

1  Synchrotron Radiation Source, SERC Daresbury Laboratory, GB-Warrington WA4 4AD, Great-Britain
2  Consiglio Nazionale delle Ricerche, Via Salaria, KM 29.500, Casella Postale 10, I-00016 Monterotondo Stazione, Roma, Italy
3  Department of Chemistry, UMIST, P.O. Box 88, GB-Manchester M60 lQD, Great-Britain


Abstract
EXAFS and XANES have provided unique and specific structural information for a number of copper proteins. Some of this work has recently been reviewed [1]. We report here the EXAFS and XANES work on superoxide dismutase in some detail to high-light some of the structural information which EXAFS and XANES have provided, and also to report on some of the recent developments for calculating multiple scattering effects in the EXAFS region. An attempt has been made to understand the high resolution XANES region of superoxide dismutase, which shows the presence of interligand scattering in addition to the strong multiple scattering from the atoms of an imidazole ring [2]. This offers an exciting possibility of investigating the stereochemical changes which accompany ligand binding or reduction of the protein.